Nanoparticles for Cancer Treatment

 


A large collaborative effort to study cancer treatment and nanoparticles is underway. 

The team is being led by Professor Wang Hui and Professor Qian Junchao. The scientists are from the Heifei Institute of Physical Science and the Chinese Academy of Sciences.

The group designed a catalytically active, photoresponsive, Fe-doped nanoparticle (FDCN). 

This has started a new branch of research, entitled chemodynamic therapy. The article was published in ACS Applied Materials & Interfaces.

The field of tumor catalytic therapy is very interested in the carbon based nanocatalyst mediated chemodynamic therapy. (CDT). However, the catalization of hydroxyl radicals (OH) from hydrogen peroxide has limited its efficiency.

To alleviate this problem, the team used very small amount of iron. The iron was added to carbon particles. The team used a solvothermal method. This improved the ability to create the necessary OH Radicals without harming the healthy cells.

Next, the team combined CDT with a different type of treatment called photothermal therapy. Therapy uses light to create heat. The heat increases the production of OH radicals. This makes the treatment even more effective. 

Testing is thorough and showed huge promise. The nanoparticles targeted cancer cells in the safe and effective way. The addition of light therapy aided in even better treatment. 

This remarkable new approach to cancer treatments opens up new doors for using carbon based nanoparticles in medicine! 

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