Nanomedicine and the Future



 Nanomedicine entails tiny drug delivery systems, approximately 1,000 times smaller than a human hair. They have been accredited as the future for disease research. However, the road from lab to patient trials has significant challenges. Researchers are looking to slash costs and reduce the time it takes to develop nanomedicine treatments. 

This research on nanomedicine was published in Nature Nanotechnology. Paul Joyce from the University of South Australia and Professor Helder Santos from the University of Groningen led the study.

The research discusses early stage recommendations for nanomedicine development during design, manufacturing, clinical, regulatory practices and much more. The hope is to maximize the chance of clinical translation. 

Paul Joyce reports recent successes in both chemotherapy and vaccines. He claims it could redefine what’s possible for in-patient care.

He reports, “ we only need to think of the recent COVID-19 pandemic to realize the acute value of nanomedicine: more than 2/3 of the global population received an mRNA vaccine to immunize against coronavirus, which was made possible by lipid nanoparticles.”

But while nanomedicines clearly represent a paradigm shift in healthcare, few have been translated to the clinic in relation to the amount of research that has been undertaken- and this has to change.

He states, “our research sets out the core principles that must be met to ensure nanomedicines can successfully overcome transitional hurdles, helping researchers, clinicians and regulatory bodies better maneuver through key steps and processes to avoid delays and enable faster clinical delivery.” 

Adherence to this framework could see a boom in the successful development of nanomedicines for a range of diseases, setting the stage for a new era of medical innovation. 

Professor Santos believes this will change the framework for the clinical delivery of medicine.

He summarizes, “ By addressing the key hurdles early on, (this approach) can lead to the next generation of personalized therapies that are tailored to individual patients, offering new hope to those desperately in need.”

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